Blar i Bergen Open Research Archive på forfatter "Gullberg, Marion Kusche"

Viser treff 1-3 av 3

    • A dominant negative splice variant of the heparan sulfate biosynthesis enzyme NDST1 reduces heparan sulfate sulfation 

      Missaghian, Parisa; Dierker, Tabea; Khosrowabadi, Elham; Axling, Fredrik; Eriksson, Inger; Ghanem, Abdurrahman; Gullberg, Marion Kusche; Kellokumpu, Sakari; Kjellén, Lena (Journal article; Peer reviewed, 2022)
      NDST1 (glucosaminyl N-deacetylase/N-sulfotransferase) is a key enzyme in heparan sulfate (HS) biosynthesis, where it is responsible for HS N-deacetylation and N-sulfation. In addition to the full length human enzyme of 882 ...

    • Heparan sulfate dependent binding of plasmatic von Willebrand factor to blood circulating melanoma cells attenuates metastasis 

      Wang, Yuanyuan; Liu, Xiaobo; Obser, Tobias; Bauer, Alexander T.; Heyes, Martin; Starzonek, Sarah; Zulal, Mina; Opitz, Karena; Ott, Leonie; Riethdorf, Sabine; Lange, Tobias; Pantel, Klaus; Bendas, Gerd; Schneider, Stefan W.; Gullberg, Marion Kusche; Gorzelanny, Christian (Journal article; Peer reviewed, 2022)
      Heparan sulfate (HS), a highly negatively charged glycosaminoglycan, is ubiquitously present in all tissues and also exposed on the surface of mammalian cells. A plethora of molecules such as growth factors, cytokines or ...

    • Integrin α11β1 in tumor fibrosis: more than just another cancer-associated fibroblast biomarker? 

      Zeltz, Cedric; Navab, Roya; Heljasvaara, Ritva Leena; Gullberg, Marion Kusche; Lu, Ning; Tsao, Ming-Sound; Gullberg, Elon Donald (Journal article; Peer reviewed, 2022)
      There is currently an increased interest in understanding the role of the tumor microenvironment (TME) in tumor growth and progression. In this context the role of integrins in cancer-associated fibroblasts (CAFs) will ...